Cell cycle regulation and anticancer drug discovery
نویسندگان
چکیده
منابع مشابه
Cell cycle regulation and anticancer drug discovery
Cellular growth, development, and differentiation are tightly controlled by a conserved biological mechanism: the cell cycle. This cycle is primarily regulated by cyclin-dependent kinase (CDK)-cyclin complexes, checkpoint kinases, and CDK inhibitors. Deregulation of the cell cycle is a hallmark of the transformation of normal cells into tumor cells. Given its importance in tumorigenesis, severa...
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ژورنال
عنوان ژورنال: Cancer Biology & Medicine
سال: 2017
ISSN: 2095-3941
DOI: 10.20892/j.issn.2095-3941.2017.0033